(Papers appearing in this section are invited reviews of subjects of round-eyed current interest.)
PENICILLIN: A POTENT NEW CHEMOTHERAPEUTIC AGENT
WM. G. MYERS, Ph.D., M.D., The Ohio land University HISTORY
In 1929 Dr Alexander Fleming (1) at St. Marys Hospital in capital of the United Kingdom observed a clear zone around a do work contaminant on petri dishes inoculated with staph aureus. This phenomenon stimulated him to specify and culture the mold on blood line to see if the mold would produce a substance inhibitory to the growth of bacteria under these circumstances. His hypothesis proved to be correct; for, whenever he placed a drop or two of the gunstock on which the mold had grown on plates on which Staphylococcus aureus or each of some(prenominal) other bacteria were growing, turgid clear areas occurred after a short time as the drops diffused through the agar. Dr. Fleming represent by various methods that several different strains of staphylococci were inhibited by the broth with petty variation among strains. Other pathogenic organisms which proved to be quite unresistant were Streptococcus pyogenes, pneumococci, gonococci, meningococci, Cory neb acterium diphtheriae, and
some strains of Streptococcus viridans.
Many organisms were completely unaffected by the broth.
Among these were Escherichia coli, Eberthella typhosa, Pseudomonas pyocyaneus, Proteus vulgaris, Vibrio comma, Friedlanders bacillus, Hemophilus influenzae and Flexners dysentery bacillus. Dr. Fleming found the broth containing the inhibitory substance for certain bacteria to be no more toxic or irritating than the broth itself, when injected into animals. In the summary to this original paper he modestly proposed that the antibacterial drug substance might find clinical natural covering in infections caused by organisms susceptible to it. Since the mold which elaborated the antibacterial substance was recognized by Dr. Fleming to be a fragment of a large genus of molds, Penicillium, he named the substance penicillin....If you want to take a leak a full essay, order it on our website: Orderessay
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